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History tells us that Nero was the Emperor who fiddled while Rome burned. PG 86 min Comedy, Music. Mammary ECM composition and function are altered by reproductive state. Fibronectin FN and laminin LN levels are increased in involution matrix I compared to nulliparous matrix Nas shown by Western blotting of mammary matrix preparations loaded by equal protein. Involution matrix shows attributes of provisional wound-healing stroma. Three-dimensional culture assays were performed in triplicate and each experiment performed in duplicate with two different batches of endogenous mammary matrix.

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Remodeling of the Mammary Microenvironment after Lactation Promotes Breast Tumor Cell Metastasis

In iiimore cells invaded in response to being precoated with involution matrix I. Having demonstrated biochemical differences in ECM isolated from quiescent and involuting glands, we next assessed whether these matrices differ functionally in their ability to influence mammosphere development in three-dimensional culture. Paul Dean has created a deadly parasite that is now attached to his stomach. Open in a separate window. Jeannie Gunn faced being the only civilised woman in an uncivilised land. Terrorists take over a plutonium bomb and threaten to detonate it in a Saudi Arabian oil field.

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